CALCIUM METABOLISM IN NEPHROSIS. I. A DESCRIPTION OF AN ABNORMALITY IN CALCIUM METABOLISM IN CHILDREN WITH NEPHROSIS

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Calcium Metabolism in Nephrosis. I. a Description of an Abnormality in Calcium Metabolism in Children with Nephrosis.

In 1923, not many years after Epstein's (1) original characterization of lipoid nephrosis, Salvesen and Linder (2) first observed a lowering of the serum calcium concentration which paralleled the decrease in serum protein level in patients with this disease.' In addition, two other features indicating a disturbance of calcium metabolism in nephrosis have been described. Boyd, Courtney, and Mac...

متن کامل

Lipoprotein metabolism in experimental nephrosis.

In experimental nephrosis, a decrease in plasma albumin resulting from proteinuria causes a decreased in the plasma oncotic pressure. The existence of an osmoreceptor, which responds to the low oncotic pressure and produces a factor(s) that signals the liver to increase the secretion of plasma proteins, is postulated. The hyperlipidemia characteristic of the nephrotic syndrome results primarily...

متن کامل

Study of calcium metabolism in Beta-Talassemia major patients

disturbances in calcium metabolism and both impairment are some of the known complications observed in beta thalassemia major patients.although iron deposition has been recognized to be the main factor for organ dysfunction in these patients,the relatively low prevalence of hypoparathyroidism has led to giving more emphasis to Ca metabolism disturbance among others.availability of more patients...

متن کامل

Calcium and Vitamin D Metabolism in Pediatric Nephrotic Syndrome; An Update on the Existing Literature

 Minimal Change Disease (MCD) is the leading cause of childhood Nephrotic Syndrome (NS). Therefore in pediatrics nephrotic syndrome, most children beyond the first year of life will be treated with corticosteroids without an initial biopsy. Children with NS often display a number of calcium homeostasis disturbances causing abnormal bone histology, including hypocalcemia, reduced serum vitamin D...

متن کامل

Pharmacokinetics of prednisolone in children with nephrosis.

The pharmacokinetics of prednisolone given intravenously were studied in 11 children with relapsed steroid responsive nephrotic syndrome, and four control subjects. The clearance of both total and unbound drug was decreased in these children and the unbound fraction of the drug in plasma was significantly correlated with the degree of hypoalbuminaemia. We conclude that changes in the clearance ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 1945

ISSN: 0021-9738

DOI: 10.1172/jci101636